National Institute of Health
Questions to Ask Before Joining a Clinical Trial
Clinical Trial Connector
Clinical trials are essential for developing new treatments for Alzheimer's, dementia, and other brain disorders. By participating, you may access cutting-edge treatments early while helping create breakthroughs for millions of others.
Sponsor: Acadia
Study Criteria: Diagnosed with AD, psychosis symptoms, age 55-95
A 6 week, multicenter, randomized,double-blind, placebo-controlled, study in patients with Alzheimer’s Disease psychosis.
A Study to Evaluate KarXT as a Treatment for Psychosis Associated With Alzheimer's Disease (ADEPT-4)
Sponsor: Bristol Myers Squibb
Study Criteria: Alzheimer’s disease, Psychosis, Add’l criteria apply
The purpose of this study is to evaluate the safety and efficacy of KarXT in adult participants with mild to severe Alzheimer's Disease (AD) with moderate to severe psychosis related to AD.
BrainGuide provides educational information about clinical trials as part of our mission to help individuals and families navigate brain health decisions. This clinical trial is featured because the study sponsor has provided financial support for UsAgainstAlzheimer’s clinical trials education efforts. UsAgainstAlzheimer’s and BrainGuide do not endorse or recommend any specific clinical trial, treatment, or sponsor, and receives no financial or other benefit from an individual’s decision to participate in a study.
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Visit BrainGuide’s Clinical Trial Connector and sign up. All details you provide are kept strictly confidential and secure through Carebox.
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Complete a brief assessment. Tell us a little about yourself or the person you’re assisting. This information helps the Clinical Trial Connector provide personalized trial matches. All details you provide are kept strictly confidential and secure through Carebox.
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Explore your personalized matches. Browse through clinical trials tailored to your profile. Each listing includes study details, requirements, and contact information. You're in complete control, connect directly with a Care Navigator by phone when you're ready, or simply save studies to review later.
Have questions? Contact us.
Participating in clinical research gives you or your loved one the opportunity to contribute to research that could lead to new treatments. Your involvement is essential to developing treatments that work for everyone, including people of different genders, races, ethnicities, and socioeconomic backgrounds. Explore the benefits, risks, and key aspects of clinical research to see if it may be a good fit for you or your loved one.
Understanding Clinical Trials
Learn the basics of clinical research, including how trials work, participant protections, informed consent, and why participation matters in advancing Alzheimer’s and dementia care.
From BrainGuide
Participating in Alzheimer’s Research
Opportunities may be available for people with Alzheimer’s,mild cognitive impairment (MCI), a family history of the disease, or those interested in brain health.
Participant & Caregiver Resources
Participation in clinical research is a personal decision. These resources can help individuals and care partners understand what to expect, questions to ask, and how to prepare for clinical trials.
Research & Innovation
Explore emerging developments in Alzheimer’s research, including biomarkers, AI-enabled research, remote and decentralized trials, and efforts to improve access and representation in research.
Diversity, Equity & Access in Research
Improving representation in Alzheimer’s research better enables discoveries and treatments to benefit all communities. Learn more about efforts to expand equitable access to research participation and dementia care.
Find a Clinical Trial
Ready to explore participation? Use MyBrainGuide’s Clinical Trial Connector 
and partner resources to learn about available studies and connect with research opportunities.
Thank you to the following companies for their generous support for our clinical trials education and awareness efforts:
To learn more about sponsorship opportunities, please contact us at: rabdu@usagainstalzheimers.org
